The BRAVE Study is a global collaboration of investigators, hospitals and patients working together to generate high-quality evidence that transforms clinical practice.
24
Countries
86
Participating Centres
3,412
Participants Enrolled
42
Peer-Reviewed Papers
BRAVE unites leading academic centres to answer a critical clinical question with rigorous, patient-focused methodology. Our multidisciplinary team spans four continents, ensuring findings generalise to diverse populations and health systems.
Randomised, adjudicated endpoints, pre-registered protocol.
Representative recruitment across countries and demographics.
Open science: results published in peer-reviewed journals.
London, UK
Berlin, DE
Paris, FR
Boston, US
Toronto, CA
Stockholm, SE
The Lancet · Mar 2026
New England Journal of Medicine · Nov 2025
